IKMB: Blood Group DB

006 KEL

The Kell blood group system consists of 36 antigens carried on a type II transmembrane glycoprotein of 732 amino acids (aka CD238). The Kell glycoprotein is a zinc-dependent metalloproteinase that has been shown to have endothelin-3-converting enzyme activity. A single disulfide bond (Kell Cys72 - XK Cys347) links the KEL protein to the XK membrane protein that carries the Kx antigen. Absence of XK leads to a reduction of expression of Kell antigens on the red blood cell membrane.

Antigens

[1] K

[2] k

[3] Kpa

[4] Kpb

[5] Ku

[6] Jsa

[7] Jsb

[8] …

[9] …

[10] Ula

[11] K11

[12] K12

[13] K13

[14] K14

[15] …

[16] K16

[17] K17

[18] K18

[19] K19

[20] Km

[21] Kpc

[22] K22

[23] K23

[24] K24

[25] VLAN

[26] TOU

[27] RAZ

[28] VONG

[29] KALT

[30] KTIM

[31] KYO

[32] KUCI

[33] KANT

[34] KASH

[35] KELP

[36] KETI

[37] KHUL

[38] KYOR

[39] KEAL

Reference Info

Gene: KEL
Allele: KEL*02
Seq: NG_007492.3 (genomic), NM_000420.3 (transcript), NP_000411.1 (protein)
Entrez GeneID: 3792
Uniprot ID: P23276
Number of exons: 19 (hg19), 19 (hg38)

KEL
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Blood Groups

006 KEL